Pozzi’s professional career began in 1950. He worked with architect Alberto Rosselli from 1963 to 1967. From 1970 to 1974, he collaborated with Achile Castiglioni and the Ponti/Fornaroli/Rosselli Studio.
His theoretical furniture is well-known. He formed Archizoom Associati, an avant-garde group in Florence, in 1966 (with Paolo Deganello and others) that brought the irony of 1960s Anti-Design to furniture design.